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Academic Journal

Hematologic Neoplasms Associated with Down Syndrome: Cellular and Molecular Heterogeneity of the Diseases.

  • Authors : Peroni E; Immunology and Molecular Oncology Unit, Veneto Institute of Oncology, IOV-IRCCS, 35128 Padova, Italy.; Gottardi M

Subjects: Down Syndrome*/Down Syndrome*/Down Syndrome*/complications ; Down Syndrome*/Down Syndrome*/Down Syndrome*/genetics ; Down Syndrome*/Down Syndrome*/Down Syndrome*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Oct 18; Vol. 24 (20). Date of Electronic Publication: 2023 Oct 18.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Batimastat Induces Cytotoxic and Cytostatic Effects in In Vitro Models of Hematological Tumors.

  • Authors : Alves R; Laboratory of Oncobiology and Hematology (LOH), University Clinics of Hematology and Oncology, Faculty of Medicine (FMUC), University of Coimbra, 3000-548 Coimbra, Portugal.; Coimbra Institute for Clinical and Biomedical Research (iCBR), Group of Environmental Genetics of Oncobiology (CIMAGO), FMUC, University of Coimbra, 3000-548 Coimbra, Portugal.

Subjects: Apoptosis*/Apoptosis*/Apoptosis*/drug effects ; Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/drug therapy ; Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/pathology

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 22; Vol. 25 (8). Date of Electronic Publication: 2024 Apr 22.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Different Levels of Therapeutic Strategies to Recover the Microbiome to Prevent/Delay Acute Lymphoblastic Leukemia (ALL) or Arrest Its Progression in Children.

  • Authors : Aronica TS; Complex Operative Unit of Clinical Pathology, ARNAS Civico Di Cristina e Benfratelli Hospitals, 90127 Palermo, Italy.; Carella M

Subjects: Microbiota* ; Gastrointestinal Microbiome* ; Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/Precursor Cell Lymphoblastic Leukemia-Lymphoma*/therapy

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 31; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 31.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

The Clinical Relevance of the EPH/Ephrin Signaling Pathway in Pediatric Solid and Hematologic Malignancies.

  • Authors : Chatzikalil E; Division of Pediatric Hematology-Oncology, First Department of Pediatrics, School of Medicine, National and Kapodistrian University of Athens, 11527 Athens, Greece.; Stergiou IE

Subjects: Clinical Relevance* ; Hematologic Neoplasms*; Humans

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 29; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 29.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Editorial & Opinion

Editorial: Multiple Myeloma: Molecular Mechanism and Targeted Therapy.

  • Authors : Bazou D; School of Medicine, University College Dublin, D04 V1W8 Dublin, Ireland.; Dowling P

Subjects: Multiple Myeloma*/Multiple Myeloma*/Multiple Myeloma*/drug therapy ; Paraproteinemias* ; Hematologic Neoplasms*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 28; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 28.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Comprehensive Molecular Profiling of NPM1-Mutated Acute Myeloid Leukemia Using RNAseq Approach.

  • Authors : Petiti J; Division of Advanced Materials Metrology and Life Sciences, Istituto Nazionale di Ricerca Metrologica (INRiM), 10135 Turin, Italy.; Pignochino Y

Subjects: Hematologic Neoplasms* ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/diagnosis ; Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/Leukemia, Myeloid, Acute*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 24; Vol. 25 (7). Date of Electronic Publication: 2024 Mar 24.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Labdane-Type Diterpenoids from Streptomyces griseorubens and Their Antimicrobial and Cytotoxic Activities.

  • Authors : Heo CS; Marine Natural Products Chemistry Laboratory, Korea Institute of Ocean Science and Technology, 385 Haeyang-ro, Yeongdo-gu, Busan 49111, Republic of Korea.; Department of Marine Technology and Convergence Engineering, Korea National University of Science and Technology (UST), 217 Gajungro, Yuseong-gu, Daejeon 34113, Republic of Korea.

Subjects: Anti-Infective Agents*/Anti-Infective Agents*/Anti-Infective Agents*/pharmacology ; Anti-Infective Agents*/Anti-Infective Agents*/Anti-Infective Agents*/therapeutic use ; Antineoplastic Agents*/Antineoplastic Agents*/Antineoplastic Agents*/therapeutic use Streptomyces griseorubens

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Mar 14; Vol. 25 (6). Date of Electronic Publication: 2024 Mar 14.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Editorial & Opinion

Special Issue "Advances in Molecular Pathogenesis and Targeted Therapies for Myeloid Neoplasms".

  • Authors : Kok CH; Precision Cancer Medicine Theme, South Australian Health & Medical Research Institute (SAHMRI), Adelaide 5000, Australia.; Adelaide Medical School, University of Adelaide, Adelaide 5000, Australia.

Subjects: Myeloproliferative Disorders*/Myeloproliferative Disorders*/Myeloproliferative Disorders*/drug therapy ; Myeloproliferative Disorders*/Myeloproliferative Disorders*/Myeloproliferative Disorders*/genetics ; Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/Myelodysplastic Syndromes*/genetics

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Feb 08; Vol. 25 (4). Date of Electronic Publication: 2024 Feb 08.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Academic Journal

Breakthrough in Blastic Plasmacytoid Dendritic Cell Neoplasm Cancer Therapy Owing to Precision Targeting of CD123.

  • Authors : Zanotta S; Hematology-Oncology and Stem-Cell Transplantation Unit, Department of Onco-Hematology and Innovative Diagnostics, Istituto Nazionale Tumori-IRCCS-Fondazione G. Pascale, 80131 Napoli, Italy.; Galati D

Subjects: Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/drug therapy ; Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/pathology ; Interleukin-3 Receptor alpha Subunit*/Interleukin-3 Receptor alpha Subunit*/Interleukin-3 Receptor alpha Subunit*/drug effects

  • Source: International journal of molecular sciences [Int J Mol Sci] 2024 Jan 25; Vol. 25 (3). Date of Electronic Publication: 2024 Jan 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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Review

Multiple Genomic Alterations, Including a Novel AFF4::IRF1 Fusion Gene, in a Treatment-Refractory Blastic Plasmacytoid Dendritic-Cell Neoplasm: A Case Report and Literature Review.

  • Authors : Sahin Y; Department of Pathology, Fox Chase Cancer Center, Philadelphia, PA 19111, USA.; Wang YL

Subjects: Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/drug therapy ; Hematologic Neoplasms*/Hematologic Neoplasms*/Hematologic Neoplasms*/genetics ; Myeloproliferative Disorders*

  • Source: International journal of molecular sciences [Int J Mol Sci] 2023 Dec 25; Vol. 25 (1). Date of Electronic Publication: 2023 Dec 25.Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067

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